We are the Cardiorespiratory Neurogenetics Laboratory at Southern Methodist University dedicated to understanding the genes and mechanisms underlying epilepsy and sudden unexpected death in epilepsy (SUDEP).
April 16-17, 2020: Congrats to Drs. Hemangini Dhaibar and Krystle Trosclair for successfully defending their PhD dissertations! They are now the 2nd and 3rd students to graduate with PhD's out of the Glasscock lab.
April 17, 2020: Congrats to Kelsey Paulhus for being first author on an invited review entitled "Clinical spectrum of KCNA1 mutations: insights into episodic ataxia and epilepsy comorbidity," our lab's first work originating at SMU. Part of her work involved mapping all known human KCNA1 single nucleotide polymorphisms and correlating them with disease phenotype, as shown below in Figure 1 of the paper.
January 24, 2020: Congrats to Krystle Trosclair for her first author publication in Neurobiology of Disease entitled "Neuron-specific Kv1.1 deficiency is sufficient to cause epilepsy, premature death, and cardiorespiratory dysregulation."
October 11, 2019: Krystle Trosclair won 1st place student poster presentation at the 6th annual Research and Industry Day Conference in Shreveport, LA for her work on the effects of neuron-specific deletion of the Kcna1 gene.
August 3, 2019: Krystle Trosclair won 2nd place poster presentation at the 18th annual Joe E. Holoubek Ark-La-Tex Cardiovascular conference for her studies of the effects of neuron-specific deletion of the Kcna1 gene.
August 1, 2019: The Glasscock lab has now moved to Southern Methodist University where Dr. Glasscock is an Associate Professor and the C. Vincent Prothro Distinguished Chair in Biological Sciences.
June 28, 2019: Dr. Glasscock published a review article entitled "Kv1.1 channel subunits in the control of neurocardiac function"
May 10, 2019: Hemangini Dhaibar won 1st place senior student poster presentation at the annual LSUHSC-S Graduate Research Day for her work on respiratory abnormalities in a mouse SUDEP model.
April 5, 2019: Congrats to Hemangini Dhaibar for her first author publication in the journal Neurobiology of Disease entitled "Cardiorespiratory profiling reveals primary breathign dysfunction in Kcna1-null mice: Implication for sudden unexpected death in epilepsy"
October 26, 2018: At the 5th annual Research and Industry Day conference, Krystle Trosclair was awarded 1st place Predoctoral Student Poster for her work on the role of neuron-specific Kv1.1 channel deficiency in epilepsy and sudden death, while Hemangini Dhaibar received an Honorable Mention for her poster on respiratory abnormalities in a mouse model of sudden death in epilepsy. We also welcomed Dr. Katharine Smith (University of Colorado-Denver), an expert in nanoscale synaptic imaging, as a guest speaker at the meeting.
September 19, 2018: Lab dinner with our guest seminar speaker Dr. Cathy Proenza (University of Colorado-Denver), an expert in the molecular physiology of cardiac pacemaking.
July 1, 2018: Dr. Glasscock was officially awarded tenure and promoted to the rank of Associate Professor.
June 14-16, 2018: Dr. Glasscock gave a lecture entitled "SUDEP in the Kv1.1 mouse model: unanswered questions" at the Imaging & Genetics Roundtable session at the Partners Against Mortality in Epilepsy (PAME) conference in Alexandria, VA. Hemangini Dhaibar also presented her research on cardiorespiratory dysfunction in Kv1.1 knockout mice during the poster session.
Edward Glasscock, Ph.D.
C. Vincent Prothro Distinguished Chair
Department of Biological Sciences
Southern Methodist University
6501 Airline Ct, Suite 113
Dallas, Texas 75206
Office: Room 338 DLSB // Phone (214) 768-4050
Lab: Room 317 DLSB // Phone (214) 768-4026
Follow us on Twitter at @GlasscockLab
*Header photo by Hemangini Dhaibar. Image depicts fluorescence-labeled hippocampal CA3 neurons in mouse brain.